Mesoporous bioactive glass particles for localized release of therapeutic ions and drugs
Investigator: Dr.-Ing. Preethi Balasubramanian (Post Doc)
Cauerstraße 6
91058 Erlangen
Raum 0.211
Tel.: 09131 85-20806
email: preethi.balasubramanian@fau.de
Betreuer: Prof. Dr. –Ing. habil. Aldo R. Boccaccini
This research project involves the synthesis of mesoporous bioactive glass nanoparticles as smart platforms for effective, non-invasive and highly targeted therapies to treat delayed bone healing and non-healing chronic skin wounds. For this purpose, mesoporous glasses are doped with specific ions which play additional roles in osteogenesis, angiogenesis and antibacterial applications [1]. Surface morphology, pore size distribution, bioactivity and in vitro cytocompatibility of the synthesized inorganic nanomatrices will be characterized. The project is being carried out in the framework of the EU funded project "MesopOrous matrices for localiZed pH-triggered releAse of theRapeuTic ions and drugs (MOZART)"
[1] A. Hoppe, V. Mouriño, and A.R. Boccaccini, “Therapeutic inorganic ions in bioactive glasses to enhance bone formation and beyond,” Biomater. Sci., 1 [3] 254–256 (2013).
